A Meta Analysis of Different Herbs (Leaves, Roots, Stems) Used in Treatment of Cancer Cells

Shivam Kumar; Keshamma E.; Utkarsh Trivedi; Deepika Janjua; Pranjal Shaw; Rohit Kumar; Roshan Kumar; Purabi Saha

doi:10.55544/jrasb.1.3.12

Authors

Shivam Kumar Department of Pharmacy, Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun-248007, Uttarakhand, INDIA.
Dr. Keshamma E. Associate Professor, Department of Biochemistry, Maharani Cluster University, Palace Road, Bangalore-560001, INDIA.
Utkarsh Trivedi Department of Pharmacy, Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun-248007, Uttarakhand, INDIA.
Deepika Janjua Department of Pharmacy, Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun-248007, Uttarakhand, INDIA.
Pranjal Shaw Department of Pharmacy, Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun-248007, Uttarakhand, INDIA.
Rohit Kumar Department of Pharmacy, Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun-248007, Uttarakhand, INDIA.
Roshan Kumar Department of Pharmacology, Dev Bhoomi Institute of Pharmacy and Research, Dehradun-248007, Uttarakhand, INDIA.
Purabi Saha Department of Pharmacy, Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun-248007, Uttarakhand, INDIA.

DOI:

https://doi.org/10.55544/jrasb.1.3.12

Keywords:

Cancer, Herbal treatment, Chemical Constituents, Alkaloids compounds

Abstract

The initial step in the progression of cancer is the deformation of normal cells, which is caused by mutations in the DNA of the cell. This abnormal cell, during the process of it’s asexual reproduction, acquires invasion characteristics and causes alterations in the tissues that are around it, while at the same time ignoring signals linked to the regulation of cell growth that are present in its immediate environment. It would appear that a significant number of the chemical compounds that are created by plants do not play any direct role in the growth of plants. These kinds of molecules are referred to by the phrase "secondary metabolite," which is short for "secondary metabolites." Essential components include alkaloids, terpenoids, flavonoids, pigments, and tannins. Secondary metabolites are responsible for a wide variety of biological effects, including those on hematopoietic cells, lipids, and the cardiovascular system. Other biological effects can also be linked to secondary metabolites.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Awuchi, Chinaza Godswill, Ikechukwu Otuosorochi Amagwula, Priyanka Priya, Roshan Kumar, Umama Yezdani, and Mohammad Gayoor Khan. "Aflatoxins in foods and feeds: A review on health implications, detection, and control." Bull. Environ. Pharmacol. Life Sci 9 (2020): 149-155.

Abdullaev F. Crocus sativus against cancer. Arch Med Res. 2003;34:354

Aggarwal B.B, Kunnumakkara A.B, Harikumar K.B, Tharakan S.T, Sung B, Anand P. Potential of spice-derived phytochemicals for cancer prevention. Planta Med. 2008;74:1560–9.

Al-Rehaily A.J, Al-Said M.S, Al-Yahya M.A, Mossa J.A, Rafatullah S. Ethnopharmacological studies on Allspice (Pimenta dioica) in laboratory animals. Pharm Biol. 2002;40:200–5.

Umama, Yezdani, G. Venkatajah, Rav Shourabh, Roshan Kumar, Arvind Verma, Ayush Kumar, and Md Khan Gayoor. "Topic-The scenario of pharmaceuticals and development of microwave as; sisted extraction technique." World J Pharm Pharm Sci 8, no. 7 (2019): 1260-1271.

Anilakumar K.R, Nagaraj N.S, Santhanam K. Effect of coriander seeds on hexachlorocyclo- hexane induced lipid peroxidation in rat liver. Nutr Res. 2001;21:1455–62.

Kumar, Roshan, Purabi Saha, Priya Lokare, Kunal Datta, P. Selvakumar, and Anurag Chourasia. "A Systemic Review of Ocimum sanctum (Tulsi): Morphological Characteristics, Phytoconstituents and Therapeutic Applications." International Journal for Research in Applied Sciences and Biotechnology 9, no. 2 (2022): 221-226.

Bar-Sela G, Epelbaum R, Schaffer M. Curcumin as an anti-cancer agent: Review of the gap between basic and clinical applications. Curr Med Chem. 2010;17:190–7.

Roshan, Kumar. "Priya damwani, Shivam kumar, Adarsh suman, Suthar Usha. An overview on health benefits and risk factor associated with coffee." International Journal Research and Analytical Review 7, no. 2 (2020): 237-249.

Sahana, Soumitra. "Purabi saha, Roshan kumar, Pradipta das, Indranil Chatterjee, Prasit Roy, Sk Abdur Rahamat." A Review of the 2019 Corona virus (COVID-19) World Journal of Pharmacy and Pharmaceutical science 9, no. 9 (2020): 2367-2381.

Bind, Amit, Saumya Das, Veena D. Singh, Roshan Kumar, Anurag Chourasia, and Purabi Saha. "Natural Bioactives For The Potential Management Of Gastric Ulceration." Turkish Journal of Physiotherapy and Rehabilitation 32, no. 3.

Dubey, Anubhav, Priyanka Yadav, Preeti Verma, and Roshan Kumar. "Investigation of Proapoptotic Potential of Ipomoea carnea Leaf Extract on Breast Cancer Cell Line." Journal of Drug Delivery and Therapeutics 12, no. 1 (2022): 51-55.

Kumar, Roshan, and Anubhav Dubey. "PHYTOCHEMICAL INVESTICATION AND HEPTOPROTECTIVE EVALUTION ACACIA RUBICA EXTRACT ISONIZED AND PARACETAMOL INDUSED ANIMAL TOXICITY." Turkish Journal of Physiotherapy and Rehabilitation 32, no. 3.

Saha, Purabi, Roshan Kumar, Richard Owusu Nyarko, Ivan Kahwa, and Paul Owusu. "HERBAL SECONDARY METABOLITE FOR GASTRO-PROTECTIVE ULCER ACTIVITY WITH API STRUCTURES." (2021).’

Nyarko, Richard Owusu, Amit Prakash, Nayan Kumar, Purabi Saha, and Roshan Kumar. "Tuberculosis a globalized disease." Asian Journal of Pharmaceutical Research and Development 9, no. 1 (2021): 198-201.

Raj, A., S. Tyagi, R. Kumar, A. Dubey, and A. C. Hourasia. "Effect of isoproterenol and thyroxine in herbal drug used as cardiac hypertrophy." Journal of Cardiovascular Disease Research (2021): 204-217.

Singh, Mukesh Kr, Ajay Kumar, Roshan Kumar, P. Satheesh Kumar, P. Selvakumar, and Anurag Chourasia. "Effects of Repeated Deep Frying on Refractive Index and Peroxide Value of Selected Vegetable Oils." International Journal for Research in Applied Sciences and Biotechnology 9, no. 3 (2022): 28-31.

Bhattacharjee S, Rana T, Sengupta A. Inhibition of lipid peroxidation and enhancement of GST activity by cardamom and cinnamon during chemically induced colon carcinogenesis in Swiss albino mice. Asian Pac J Cancer Prev. 2007;8:578–82.

Bode A.M, Ma W.Y, Surh Y.J, Dong Z. Inhibition of epidermal growth factor-induced cell trans-formation and activator protein 1 activation by [6]-gingerol. Cancer Res. 2001;61:850–3.

Bar-Sela G, Epelbaum R, Schaffer M. Curcumin as an anti-cancer agent: Review of the gap between basic and clinical applications. Curr Med Chem. 2010;17:190–7.

Awuchi, C. G., Amagwula, I. O., Priya, P., Kumar, R., Yezdani, U., & Khan, M. G. (2020). Aflatoxins in foods and feeds: A review on health implications, detection, and control. Bull. Environ. Pharmacol. Life Sci, 9, 149-155.

Umama, Y., Venkatajah, G., Shourabh, R., Kumar, R., Verma, A., Kumar, A., & Gayoor, M. K. (2019). Topic-The scenario of pharmaceuticals and development of microwave as; sisted extraction technique. World J Pharm Pharm Sci, 8(7), 1260-1271.

Kumar, R., Saha, P., Lokare, P., Datta, K., Selvakumar, P., & Chourasia, A. (2022). A Systemic Review of Ocimum sanctum (Tulsi): Morphological Characteristics, Phytoconstituents and Therapeutic Applications. International Journal for Research in Applied Sciences and Biotechnology, 9(2), 221-226.

Daharia, A., Jaiswal, V. K., Royal, K. P., Sharma, H., Joginath, A. K., Kumar, R., & Saha, P. (2022). A Comparative review on ginger and garlic with their pharmacological Action. Asian Journal of Pharmaceutical Research and Development, 10(3), 65-69.

Saha, P., Nyarko, R. O., Lokare, P., Kahwa, I., Boateng, P. O., & Asum, C. (2022). Effect of Covid-19 in Management of Lung Cancer Disease: A Review. Asian Journal of Pharmaceutical Research and Development, 10(3), 58-64.

Kumar, R., & Saha, P. (2022). A Review on Artificial Intelligence and Machine Learning to Improve Cancer Management and Drug Discovery. International Journal for Research in Applied Sciences and Biotechnology, 9(3), 149-156.

Saha, P., Kumar, A., Bhanja, J., Shaik, R., Kawale, A. L., & Kumar, R. (2022). A Review of Immune Blockade Safety and Antitumor Activity of Dostarlimab Therapy in Endometrial Cancer. International Journal for Research in Applied Sciences and Biotechnology, 9(3), 201-209.

Kumar, R., Keshamma, E., Paswan, S. K., Saha, P., Trivedi, U., Chourasia, A., & Otia, M. (2022). Alkaloid Based Chemical Constituents of Ocimum santum & Cinchona Bark: A Meta Analysis. Journal for Research in Applied Sciences and Biotechnology, 1(2), 35-42.

Singh, Y., Paswan, S. K., Kumar, R., Otia, M. K., Acharya, S., Kumar, D., & Keshamma, E. (2022). Plant & Its Derivative Shows Therapeutic Activity on Neuroprotective Effect. Journal for Research in Applied Sciences and Biotechnology, 1(2), 10-24.

Nyarko, R. O., Roopini, R., Raviteja, V., Awuchi, C. G., Kumar, R., Faller, E. M., ... & Saha, P. (2022). Novel Sars-CoV-2 Variants & Therapeutic Effects. Journal for Research in Applied Sciences and Biotechnology, 1(2), 25-34.

Saha, P., Kumar, R., Nyarko, R. O., Kahwa, I., & Owusu, P. (2021). HERBAL SECONDARY METABOLITE FOR GASTRO-PROTECTIVE ULCER ACTIVITY WITH API STRUCTURES.

Roshan, K. (2020). Priya damwani, Shivam kumar, Adarsh suman, Suthar Usha. An overview on health benefits and risk factor associated with coffee. International Journal Research and Analytical Review, 7(2), 237-249.

Dubey, A., Yadav, P., Verma, P., & Kumar, R. (2022). Investigation of Proapoptotic Potential of Ipomoea carnea Leaf Extract on Breast Cancer Cell Line. Journal of Drug Delivery and Therapeutics, 12(1), 51-55.

Sahana, S. (2020). Purabi saha, Roshan kumar, Pradipta das, Indranil Chatterjee, Prasit Roy, Sk Abdur Rahamat. A Review of the 2019 Corona virus (COVID-19) World Journal of Pharmacy and Pharmaceutical science, 9(9), 2367-2381.

Bind, A., Das, S., Singh, V. D., Kumar, R., Chourasia, A., & Saha, P. Natural Bioactives For The Potential Management Of Gastric Ulceration. Turkish Journal of Physiotherapy and Rehabilitation, 32(3).

Nyarko, R. O., Prakash, A., Kumar, N., Saha, P., & Kumar, R. (2021). Tuberculosis a globalized disease. Asian Journal of Pharmaceutical Research and Development, 9(1), 198-201.

Raj, A., Tyagi, S., Kumar, R., Dubey, A., & Hourasia, A. C. (2021). Effect of isoproterenol and thyroxine in herbal drug used as cardiac hypertrophy. Journal of Cardiovascular Disease Research, 204-217.

Kumar, R., & Dubey, A. PHYTOCHEMICAL INVESTICATION AND HEPTOPROTECTIVE EVALUTION ACACIA RUBICA EXTRACT ISONIZED AND PARACETAMOL INDUSED ANIMAL TOXICITY. Turkish Journal of Physiotherapy and Rehabilitation, 32(3).

Singh, M. K., Kumar, A., Kumar, R., Kumar, P. S., Selvakumar, P., & Chourasia, A. (2022). Effects of Repeated Deep Frying on Refractive Index and Peroxide Value of Selected Vegetable Oils. International Journal for Research in Applied Sciences and Biotechnology, 9(3), 28-31.

Saha, P., Kumar, R., Nyarko, R. O., Kahwa, I., & Owusu, P. (2021). HERBAL SECONDARY METABOLITE FOR GASTRO-PROTECTIVE ULCER ACTIVITY WITH API STRUCTURES.

Nyarko, R. O., Kumar, R., Sharma, S., Chourasia, A., Roy, A., & Saha, P. (2022). ANTIBACTERIAL ACTIVITY OF HERBAL PLANT-TINOSPORA CORDIFOLIA AND CATHARNTHUS ROSEUS.

Sahana, S., Kumar, R., Nag, S., Paul, R., Chatterjee, I., & Guha, N. (2020). A REVIEW ON ALZHEIMER DISEASE AND FUTURE PROSPECTS.

Sahana, S. (2020). Roshan kumar, Sourav nag, Reshmi paul, Nilayan guha, Indranil Chatterjee. A Review on Alzheimer disease and future prospects. World Journal of Pharmacy and Pharmaceutical science, 9(9), 1276-1285.

Nyarko, R. O., Saha, P., Kumar, R., Kahwa, I., Boateng, E. A., Boateng, P. O., ... & Bertram, A. (2021). Role of Cytokines and Vaccines in Break through COVID 19 Infections. Journal of Pharmaceutical Research International, 33, 2544-2549.

PURABISAHA, R. K., RAWAT, S. S. N., & PRAKASH, A. (2021). A REVIEW ON NOVEL DRUG DELIVERY SYSTEM.

Nyarko, R. O., Boateng, E., Kahwa, I., & Boateng, P. O. (2020). A comparison analysis on remdesivir, favipiravir, hydroxychloroquine, chloroquine and azithromycin in the treatment of corona virus disease 2019 (COVID-19)-A Review. World J. Pharm. Pharm. Sci, 9, 121-133.

KUMAR, R., SAHA, P., SARKAR, S., RAWAT, N., & PRAKASH, A. (2021). A REVIEW ON NOVEL DRUG DELIVERY SYSTEM. IJRAR-International Journal of Research and Analytical Reviews (IJRAR), 8(1), 183-199.

Nyarko, R. O., Boateng, E., Kahwa, I., Boateng, P. O., & Asare, B. (2020). The impact on public health and economy using lockdown as a tool against COVID-19 pandemic in Africa: a perspective. J Epidemiol Public Health Rev, 5(3).

Kumar, R., Saha, P., Pathak, P., Mukherjee, R., Kumar, A., & Arya, R. K. EVOLUTION OF TOLBUTAMIDE IN THE TREATMENT OF DIABETES MELLITUS. Jour. of Med. P’ceutical & Alli. Sci, 9.

Kumar, R., Saha, P., Kumar, Y., Sahana, S., Dubey, A., & Prakash, O. (2020). A Review on Diabetes Mellitus: Type1 & Type2. World Journal of Pharmacy and Pharmaceutical Sciences, 9(10), 838-850.

Daharia, A., Jaiswal, V. K., Royal, K. P., Sharma, H., Joginath, A. K., Kumar, R., & Saha, P. (2022). A Comparative review on ginger and garlic with their pharmacological Action. Asian Journal of Pharmaceutical Research and Development, 10(3), 65-69.

Saha, P., Nyarko, R. O., Lokare, P., Kahwa, I., Boateng, P. O., & Asum, C. (2022). Effect of Covid-19 in Management of Lung Cancer Disease: A Review. Asian Journal of Pharmaceutical Research and Development, 10(3), 58-64.

Kumar, R., Keshamma, E., Paswan, S. K., Saha, P., Trivedi, U., Chourasia, A., & Otia, M. (2022). Alkaloid Based Chemical Constituents of Ocimum santum & Cinchona Bark: A Meta Analysis. Journal for Research in Applied Sciences and Biotechnology, 1(2), 35-42.

Nyarko, R. O., Roopini, R., Raviteja, V., Awuchi, C. G., Kumar, R., Faller, E. M., ... & Saha, P. (2022). Novel Sars-CoV-2 Variants & Therapeutic Effects. Journal for Research in Applied Sciences and Biotechnology, 1(2), 25-34.

KUMAR, A. (2019). The Scenario of Pharmaceuticals and Development of Microwave Assisted Extraction Techniques.

Kumar, R., & Saha, P. (2022). A Review on Artificial Intelligence and Machine Learning to Improve Cancer Management and Drug Discovery. International Journal for Research in Applied Sciences and Biotechnology, 9(3), 149-156.

Kumar, R., Keshamma, E., Paswan, S. K., Saha, P., Trivedi, U., Chourasia, A., & Otia, M. (2022). Alkaloid Based Chemical Constituents of Ocimum santum & Cinchona Bark: A Meta Analysis. Journal for Research in Applied Sciences and Biotechnology, 1(2), 35-42.

Nyarko, R. O., Roopini, R., Raviteja, V., Awuchi, C. G., Kumar, R., Faller, E. M., ... & Saha, P. (2022). Novel Sars-CoV-2 Variants & Therapeutic Effects. Journal for Research in Applied Sciences and Biotechnology, 1(2), 25-34.

Mukkamala, R., Kumar, R., Banerjee, S. K., & Aidhen, I. S. (2020). Synthesis of Benzyl C‐Analogues of Dapagliflozin as Potential SGLT2 Inhibitors. European Journal of Organic Chemistry, 2020(12), 1828-1839.

Bhati, V., Yadav, P. K., & Kumar, R. (2018). Effect of Levels of Inorganic Fertilizers, Organic Manure and Bio-Fertilizers on Plant Growth Attributes of Onion (Allium cepa L.) cv. N-53 under Hot Arid Region of Western Rajasthan, India. International J. Curr. Micro. Appl. Sci, 7, 3593-601.

Bugga, P., Alam, M. J., Kumar, R., Pal, S., Chattopadyay, N., & Banerjee, S. K. (2022). Sirt3 ameliorates mitochondrial dysfunction and oxidative stress through regulating mitochondrial biogenesis and dynamics in cardiomyoblast. Cellular Signalling, 94, 110309.

Kumar, S., Yadav, S. P., Chandra, G., Sahu, D. S., Kumar, R., Maurya, P. S., ... & Ranjan, K. (2019). Effect of dietary supplementation of yeast (Saccharomyces cerevisiae) on performance and hemato-biochemical status of broilers.

Kumar, R., Saha, P., Keshamma, E., Sachitanadam, P., & Subramanian, M. (2022). Docking Studies of Some Novel Hetrocyclic Compound as Acat Inhibitors: A Meta Analysis. Journal for Research in Applied Sciences and Biotechnology, 1(3), 33-41.

Amle, V. S., Rathod, D. A., Keshamma, E., Kumar, V., Kumar, R., & Saha, P. (2022). Bioactive Herbal Medicine Use for Eye Sight: A Meta Analysis. Journal for Research in Applied Sciences and Biotechnology, 1(3), 42-50.

Pandey, M., Singh, A., Agnihotri, N., Kumar, R., Saha, P., Pandey, R. P., & Kumar, A. (2022). Clinical Pharmacology & Therapeutic uses of Diuretic Agents: A Review. Journal for Research in Applied Sciences and Biotechnology, 1(3), 11-20.

Anubhav, S. P. D., Sanjay, K. D., & Roshan, K. (2022). Evaluation of Enzyme Producing K. Pneumoniae and Their Susceptibility to Other Anti-Biotics. International Journal of Innovative Science and Research Technology2022, 7(5), 351-353.