Treatment of Psoriasis with the Help of Curcumin Hydrogel

Authors

  • Yash Gupta Dr. MC Saxena College of Pharmacy, Lucknow, Uttar Pradesh, INDIA.
  • Neeraj Kumar Institute of Pharmaceutical Sciences & Research Unnao, Kanpur, Uttar Pradesh, INDIA.
  • Amrita Shukla Dr. MC Saxena College of Pharmacy, Lucknow, Uttar Pradesh, INDIA.
  • Vishal Rai Dr. MC Saxena College of Pharmacy, Lucknow, Uttar Pradesh, INDIA.

DOI:

https://doi.org/10.55544/jrasb.2.2.32

Keywords:

Psoriasis, Inflammatory skin disorder, Antioxidant properties, Curcumin hydrogel

Abstract

Psoriasis is a chronic inflammatory skin disorder that affects millions of people worldwide. Current treatments for psoriasis include topical corticosteroids, immunomodulators, and phototherapy, but these treatments may have limited efficacy or cause side effects. Curcumin, a natural compound with anti-inflammatory and antioxidant properties, has been shown to have potential as an alternative treatment for psoriasis. However, the low solubility and bioavailability of curcumin limit its effectiveness when administered orally or topically. Curcumin hydrogel, a topical formulation of curcumin, has been developed to address these limitations. In this review, we summarize the current research on the use of curcumin hydrogel in the treatment of psoriasis. We discuss the pharmacological properties of curcumin, the formulation of curcumin hydrogel, and the preclinical and clinical studies investigating the efficacy and safety of curcumin hydrogel in psoriasis. Overall, the available evidence suggests that curcumin hydrogel may be a promising alternative treatment for psoriasis, with potential benefits in reducing inflammation, promoting wound healing, and improving overall quality of life for psoriasis patients. Further research is needed to fully elucidate the mechanism of action of curcumin hydrogel and to optimize its formulation and delivery for maximum efficacy.

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Dubey A, Dash SL, Kumari P, Patel S, Singh S, Agarwal S, A Comprehensive Review on Recent Progress in Invivo and Invitro Models for Hyperlipidemia Studies. Pakistan Heart Journal, 2023:56(01),286-297. http://www.pkheartjournal.com.

Anubhav Dubey, Niladry Sekhar Ghosh, Anubha Gupta, Shweta Singh, 2023. A review on current epidemiology and molecular studies of lumpy skin disease virus-an emerging worldwide threat to domestic animals. Journal of medical pharmaceutical and allied sciences, V 12 - I 1, Pages - 5635 – 5643.DOI: 10.55522/jmpas.V12I1.4583.

Pate S, Dubey A, Gupta Ak, Ghosh NS, (2023). Evaluation of Antimicrobial Activity of Calotropis Gigantea Extracts on Two Main Skin Infection Causing Bacteria - Escherichia Coli and Staphylococcus Aureus.12(1):145-157.

Dubey A, Ghosh NS, Singh R. Zebrafish as An Emerging Model: An Important Testing Platform for Biomedical Science. J Pharm Negative Results 2022;13(3): 1-7.DOI:10.47750/pnr.2022.13.03.001.

Anubhav Dubey, Raghuvendra Singh, Ashish Kumar, Gaurav Mishra, Anubha Gupta, Anuj Sonker, & Amit Mishra. (2022). A Critical Review on Changing Epidemiology of Human Monkeypox-A Current Threat with Multi-Country Outbreak. Journal of Pharmaceutical Negative Results, 660–671. Retrieved from https://www.pnrjournal.com/index.php/home/article/view/738.

Dubey, A., Yadav, P., Peeyush, , Verma, P., & Kumar, R. (2022). Investigation of Proapoptotic Potential of Ipomoea carnea Leaf Extract on Breast Cancer Cell Line. Journal of Drug Delivery and Therapeutics, 12(1), 51-55. https://doi.org/10.22270/jddt.v12i1.5172

Dubey Anubhav Ghosh Sekhar Niladry, Saxena Gyanendra Kumar, Purohit Debashis, Singh Shweta, (2022) .Management implications for neurotoxic effects associated with antibiotic use. NeuroQuantology, 6(20), 304-328. doi: 10.14704/nq.2022.20.6.NQ22034.

Dubey, A., Ghosh, N. S., Rathor, V. P. S., Patel, S., Patel, B., &Purohit, D. (2022).Sars- COV-2 infection leads to neurodegenerative or neuropsychiatric diseases. International Journal of Health Sciences, 6(S3), 2184–2197. DOI: https://doi.org/10.53730/ijhs.v6nS3.5980.

Kumar, A.., Dubey, A.., & Singh, R.. (2022). Investigation on Anti-Ulcer Activity of Momordica dioica Fruits in Wistar Rat. International Journal for Research in Applied Sciences and Biotechnology, 9(1), 105–111. https://doi.org/10.31033/ijrasb.9.1.12

Dubey Anubhav, Tiwari Mamta, Kumar Vikas, Srivastava, Kshama, Singh, Akanksha. Investigation of Anti-Hyperlipidemic Activity of Vinpocetine in Wistar Rat.International Journal of Pharmaceutical Research 2020; 12(02):1879-1882. DOI: https://doi.org/10.31838/ijpr/2020.12.02.250.

Raj Pratap Singh , Dr. Vishal Dubey ,Anubhav Dubey & Dr. Shantanu, Liposomal gels for vaginal drug delivery of Amoxicillin Trihydrate, International Journal of Medical Research and Pharmaceutical Sciences;2020 7(8) 1-13.

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Published

2023-05-13

How to Cite

Gupta, Y., Kumar, N., Shukla, A., & Rai, V. (2023). Treatment of Psoriasis with the Help of Curcumin Hydrogel. Journal for Research in Applied Sciences and Biotechnology, 2(2), 224–230. https://doi.org/10.55544/jrasb.2.2.32

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