Investigation of Anti- Pyretic Activity of Cinnamon Oil in Wistar Rat

Gaurava Srivastav; Dakshina Gupta; Anubhav Dubey; Neeraj Kumar

doi:10.55544/jrasb.1.3.7

Authors

Gaurava Srivastav Research Scholar, Department of Pharmacology, Advance Institute of Biotech and Paramedical Sciences, Kanpur, (U.P.), INDIA.
Dakshina Gupta Assistant Professor, Department of Pharmacology, Advance Institute of Biotech and Paramedical Sciences, Kanpur (U.P.), INDIA.
Anubhav Dubey Assistant Professor, Department of Pharmacology, Maharana Pratap College of Pharmacy, Kanpur (U.P.), INDIA.
Neeraj Kumar Assistant Professor, Department of Pharmaceutics, Dr. M. C. Saxena College of Pharmacy, Lucknow (U.P.), INDIA.

DOI:

https://doi.org/10.55544/jrasb.1.3.7

Keywords:

Lipopolysaccharides, Brewer’s yeast, Cinnamon oil, Pyrexia

Abstract

The current exploration work was to explore the antipyretic movement of cinnamon oil (25 Milligram/ kilogram or 50 Milligram/ kilogram p.o). The antipyretic movement was assessed against Brewer's yeast and lipopolysaccharides instigated pyrexia in rodents. In case of lipopolysaccharides instigated pyrexia (50 mg/kg, p.o) is more effective comparison to 25 Milligram/ kilogram. But in case of Brewer's yeast induced pyrexia both low and high dose is more effective of cinnamon oil (25 mg/kg or 50 Milligram/ kilogram p.o) suppress anal temperature significantly 96.42 ± 0.009 and 95.40 ± 0.000 respectively in Brewer’s yeast instigated pyrexia. The exploration result shows that cinnamon oil (25 Milligram/ kilogram or 50 Milligram/ kilogram, p.o) is having a huge enemy of antipyretic potential.

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References

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