Evaluation of the Effect of Tagetes erecta Leaves Hydroalcoholic Extract on Blood Clotting Time

Authors

  • Sourav Roy Assistant Professor, Department of Pharmacology, Netaji Subhas Chandra Bose Institute of Pharmacy, Chakdaha, Nadia-741222, West Bengal, INDIA.
  • Mrityunjoy Majumdar Professor (HOD), Department of Pharmacology, Netaji Subhas Chandra Bose Institute of Pharmacy, Chakdaha, Nadia-741222, West Bengal, INDIA.
  • Prodip Roy Assistant Professor, Department of Pharmacology, Netaji Subhas Chandra Bose Institute of Pharmacy, Chakdaha, Nadia-741222, West Bengal, INDIA.
  • Sanjoy Saha Student, Netaji Subhas Chandra Bose Institute of Pharmacy, Chakdaha, Nadia-741222, West Bengal, INDIA.
  • Suranjanaa Das Student, Netaji Subhas Chandra Bose Institute of Pharmacy, Chakdaha, Nadia-741222, West Bengal, INDIA.
  • Mon Dey Student, Netaji Subhas Chandra Bose Institute of Pharmacy, Chakdaha, Nadia-741222, West Bengal, INDIA.
  • Pratyush Porel Student, Netaji Subhas Chandra Bose Institute of Pharmacy, Chakdaha, Nadia-741222, West Bengal, INDIA.

DOI:

https://doi.org/10.55544/jrasb.2.2.16

Keywords:

Tagetes erecta, hydro alcoholic extract, Tranexamic Acid, blood clotting time

Abstract

People were afflicted with a variety of illnesses prior to the revolution, and there was no access to medications sufficiently, at that time herbal agents fulfilled the demand for medications. In these modern days due to the huge side effects as well as drug resistance of marketed drugs, the demand for herbal medicines is increasing.

We are all busy in our lives these days, we are traveling here and there to maintain our social duties. Due to this, the number of accidents is increasing around us.

When a blood vessel is injured, blood clotting, or coagulation, is a crucial process that reduces excessive bleeding. So, the drugs that are able to reduce clotting time are essential for us.

In this research we evaluated the blood clotting effect of two different doses (250mg/kg and 500mg/kg) of Tagetes erecta leaves hydroalcoholic extract on the albino wistar rat, and compared the effect with a marketed standard drug Tranexamic Acid (Pause 500 mg).

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References

Roy P, Das H, Ali MS, Sarkar P, Chattopadhyay S. a review on Paederia foetida as a medicinal plant and it's pharmacological activities. World Journal of Pharmacy and Pharmaceutical Sciences.2021;10(12): 637-647

Saha A, Chatterjee A, Singh S, Ghosh J, Majumdar M, Roy S, Roy P. Herbal Agents Having Abortive Activity. Journal for Research in Applied Sciences and Biotechnology. 2022 Aug 31;1(3):204-15.

Samadder SS, Singh S, Saha A, Chatterjee A, Majumdar M, Roy S, Roy P. Preclinical Evaluation of Tropic Activity on Isolated Frog Heart by Using Volatile Oil of Nigella sativa Seeds. Journal for Research in Applied Sciences and Biotechnology. 2022 Oct 31;1(4):1-4.

Roy P, Pramanick K, Das A, Majumdar M, Roy A, Sarkar U. Review of Some Herbal Agents Having Antiviral Activity. International Journal of Current Science Research and Review.2022;5(3):695-706

Chattopadhyay S, Roy P, Mandal D. A Review on Cucumis sativus L. and its Anti-Ulcer Activity. Journal for Research in Applied Sciences and Biotechnology. 2023 Mar 3;2(1):201-3.

Majumdar M, Samanta A, Roy A. Study of wound healing activity of different formulations of Nigella sativa seed extract. Research Journal of Pharmacy and Technology. 2016;9(12):2097-105.

Waugh A, Grant A. Ross & Wilson Anatomy and physiology in health and illness E-book. Elsevier Health Sciences; 2014 Jun 25.

Parasuraman S, Zhen KM, Raveendran R. Retro-orbital sample collection in Rats-a video article. Pharmacology, Toxicology and Biomedical Reports. 2015;1(2).

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Published

2023-04-25

How to Cite

Roy , S., Majumdar, M., Roy, P., Saha , S., Das , S., Dey , M., & Porel, P. (2023). Evaluation of the Effect of Tagetes erecta Leaves Hydroalcoholic Extract on Blood Clotting Time. Journal for Research in Applied Sciences and Biotechnology, 2(2), 115–117. https://doi.org/10.55544/jrasb.2.2.16

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