Review Article: Effect Anticancer Drug of Histological Alteration and Improvement their Effects by Natural Antioxidants

Authors

  • Raghad Jawad Salman Department of Anatomy and Medical biology, Medicine College, Wasit University, IRAQ.
  • Roaa M. H. Shoker Department of Pharmacology, Medicine College, Wasit University, IRAQ.
  • Hakim Bahlok Jebur Department of Pharmacology, Medicine College, Wasit University, IRAQ.

DOI:

https://doi.org/10.55544/jrasb.2.4.22

Keywords:

Anticancer drugs, Free radicals, Natural antioxidants

Abstract

Usually, Cancer and anticancer drugs can produce harmful side effects, side effects which occur in tissues or organs and produce adverse histopathological change. Cancer treatment by radiotherapy and chemotherapy, and chemotherapy treatments is more mostly used all over the world. Generally, chemotherapy drugs cusses the damage by free radicals and produce cytotoxicity. Natural antioxidant compounds of daily diet are more effective to scavenge or neutralize the free radicals which create by chemotherapy drugs and finally, improvement histopathological change.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Shi, H.; Y. Chang; Y. Gao; X. Wang; X. Chen; Y. Wang; C. Xue, and Q.Tang. 2017. Dietary fucoidan of Acaudina molpadioides alters gut microbiota and mitigates intestinal mucosal injury induced by cyclophosphamide. Food and function, 8: 3383-3393.

Bonadonna, G.; P. Valagussa; A. Moliterni; M. Zambetti, and C. Brambilla.1995. Adjuvant cyclophosphamide, methotrexate, and fluorouracil in node-positive breast cancer: the results of 20 years of follow-up. N Engl J Med, 332:901-906.

de Graaf, H.; P.H. Willemse; S.B.Bong; H. Piersma; T. Tjabbes; H.van Veelen; J.L.Coenen, and E.G.de Vries.1996. Dose intensity of standard adjuvant CSF with granulocyte colony-stimulating factor for premenopausal patients with node-positive breast cancer. Oncology, 53:289-294.

Abdella, E. 2008. Bacterial lipopolysaccharides pretreatment protects against mutagenic and immunosuppress or effects of cyclophos-phamide in mice. Iran J Cancer Prev., 4(1): 155-65.

Khan, f.; V.K. Garg; A.K. Singh, and T. Kumar.2018. Role of free radicals and certain antioxidants in the management of huntington’s disease: a review. J Anal Pharm Res., 7(4): 386-392.

Pham-Huy, L.A.; H. Hua, and C. Pham-Huy. 2008. Free Radicals, Antioxidants in Disease and Health. Int J Biomed Sci.,4(2):89-96.

Shoker, R.M.H.; W.H. Al-Shammery, and S.R. Al-Aidy. 2023. A Review Article: Free Radical and Replacement Synthetic Antioxidant by Natural Antioxidant . Volume-2 Issue-2, PP. 206-211.

Dickson, M.A. and G.K. Schwartz. 2009. Development of cell-cycle inhibitors for cancer therapy. Curr Oncol., 16:36–43.

Azadmehr, A.; R. Hajiaghaee; A. Afshari; Z. Amirghofran; M. Refieian-Kopaei; H. Yousofi-Darani, and H. Shirzad. 2011. Evaluation of in vivo immune response activity and in vitro anti-cancer effect by Scrophularia megalantha. J Med Plants Res., 21: 2365-2368.

Hassan, B. A. R. 2012. Medicinal Plants (importance and uses .(Clinical pharmacy discipline, school of pharmaceutical sciences, University of Sains Malaysia, Malaysia .

Kumar, S.; S. Paul; Y. K. Walia; A. Kumar, and P. Singhal. 2015. Therapeutic potential of medicinal plants: A Review J Biol Chem Chron., 1(1), 46-54.

Alamgir, A.N.M. 2018. Therapeutic use of medicinal plants and their extracts. University of Chittagong. Springer International Publishing. Volume 2.

Fontana, R.J. 2014. Pathogenesis of idiosyncratic drug-induced liver injury and clinical perspectives. Gastroenterology, 146:914-928.

Hoofnagle, J. H. and E. S. Björnsson . 2019. Drug-induced liver injury-types and phenotypes. New N Engl J Med., 381: 264-273.

MacSween, R.N.M.; V.J. Desmet; T. Roskams, and R.J. Scothorne. 2002. Developmental anatomy and normal structure. Pathology of the liver, pp. 1

Roy-Chowdhury, N. and J. Roy-Chowdhury. 2006. Liver Physiology and Energy Metabolism. In: M. Feldman; L.S.Friedman, and L.J. Brandt (eds.). Gastrointestinal and Liver Disease. 2nd. Ed. Philadelphia, p. 1551.

Yuan, J.N.; Y. Chao; W.P. Lee; C.P. Li; R.C. Lee; F.Y. Chang; S.H. Yen; S.D. Lee, and J. Whang-Peng. 2008. Chemotherapy with etoposide, doxorubicin, cisplatin, 5-fluorouracil, and leucovorin for patients with advanced hepatocellular carcinoma. Med Oncol, 25 (2):201-206.

Lin, C.C.; C.H. Hsu; C.Y. Huang; A.L. Cheng; J. Chen; N.J. Vogelzang, and Y.S. Pu. 2006. Weekly cisplatin plus infusional high-dose 5-fluorouracil and leucovorin (P-HDFL) for metastatic urothelial carcinoma: an effective regimen with low toxicity. Cancer, 106:1269-75.

El-Sayyad, H.I; M. F Ismail; F. M. Shalaby; R.F. Abou-El-Magd; R. L. Gaur; A. Fernando; M. H.G. Raj, and A. Ouhtit. 2009. Histopathological effects of cisplatin, doxorubicin and 5-flurouracil (5-FU) on the liver of rats. Int J Biol Sci., 5(5):466-473.

Ledda-Columbano, G.M.; P. Coni; M. Curto; L. Giacomini; G. Faa; S. Oliverio; M. Piacentini, and A. Columbano. 1991. Induction of two different modes of cell death, apoptosis and necrosis, in rat liver after a single dose of thioacetamide. Am J Pathol, 139:1099-1109.

Kikuchi, K.; R. Rudolph; C. Murakami; K. Kowdley, and G.B. McDonald. 2002. Portal vein thrombosis after hematopoietic cell transplantation: frequency, treatment and outcome. Bone Marrow Transplant, 29:329-333.

Shokrzadeh, M.; A. Ahmadi; F. Naghshvar; A. Chabra, and M. Jafarinejhad. 2014. Prophylactic efficacy of melatonin on Cyclophosphamide-induced liver toxicity in mice. Bio Med Research International, 6 pages.

Al-Salih, H.A.; N. M. Al-Sharafi; S. S. Al-Qabi, and A. A. Al-Darwesh. 2020. The Pathological Features of Cyclophosphamide Induced Multi-Organs Toxicity in Male Wister Rats. Sys Rev Pharm, 11(6): 45- 49.

Moriya, A.; I. Hyodo; T. Nishina; H. Imaoka; A. Imagawa; T. Doi; H.Endo; M. Tanimizu, and H. Tajiri.2000. Extensive liver metastasis of gastric cancer effectively treated by hepatic arterial infusion of 5-fluorouracil/ cisplatin. Gastric Cancer, 3:110-115.

Devlin, T.M. 1997. Text book of biochemistry: with clinical correlation, 4th ed. New York: John Wiley and Sons Inc; 553.

Kaplowitz, N. 2007. Drug induced liver disease. Informa Health Care, pp. 115.

Kaplowitz, N. 2001. Causality assessment versus guilt-by-association in drug hepatotoxicity. Hepatology, 33, pp. 308-310.

Lucena, M.I.; R. Camargo; R.J.Andrade; C.J. Perez-Sanchez, D.L.C.Sanchez. 2001.Comparison of two clinical scales for causality assessment in hepatotoxicity. Hepatology, 33,pp. 123-130.

Santos, M.L.C.; B.B. Brito; F.A.F. da Silva; A.C.D.S. Botelho, and F.F. Melo. 2020. Nephrotoxicity in cancer treatment: An overview. World J Clin Oncol., 11(4): 190-204.

Izzedine, H. and M. A. Perazella. 2017. Anticancer Drug-Induced Acute Kidney Injury. Kidney Int Rep., 2(4): 504-514.

Jhaveri,K.D., and S. Fishbane.2013. Nephrology Crossword: Onco-nephrology-chemotherapy agents and nephrotoxicity. Kidney Int., 84:421-422.

Lameire, N. 2014. Nephrotoxicity of recent anti-cancer agents. Clin Kidney J., 7(1): 11–22.

Al-Salih, H. A.; N. M. Al-Sharafi; S. S.Al-Qabi, and A. A. Al-Darwesh. 2020. The Pathological Features of Cyclophosphamide Induced Multi-Organs Toxicity in Male Wister Rats. Sys Rev Pharm.,11(6): 45 - 49.

Izzedine, H. and M. A. Perazella. 2017. Anticancer Drug-Induced Acute Kidney Injury. Kidney Int Rep., 2(4): 504-514.

Jia, J.B.; C. Lall; T.Tirkes; R. Gulati; R. Lamba, and C. Scott. 2015. Goodwin1 Chemotherapy-related complications in the kidneys and collecting. Insights Imaging, 6:479-487.

Izzedine, H.; V.Gueutin; C. Gharbi; C.Mateus; C. Robert C; E. Routier; M. Thomas; A.Baumelou, and P. Rouvier. 2014. Kidney injuries related to ipilimumab. Investig NewDrugs 32(4):769-773.

Xie, J.; S. Nie; Q. Yu; J. Yin; T. Xiong; D. Gong; M.J.J. O. A. Xie, and F.chemistry. 2016. Lactobacillus plantarum NCU116 attenuates cyclophosphamide-induced immunosuppression and regulates Th17/Treg cell immune responses in mice. J Agric Food Chem., 64: 1291-1297.

Nabil, M.; E. E.Hassan; N.S. Ghaly; F.A. Aly; F.R Melek; Z.M. Hassan; M.A. Fahmy, and A. A.Farghaly. 2020. Albizia chinensis bark extract ameliorates the genotoxic effect of cyclophosphamide. Bulletin of the National Research Centre., 44, 165.

Madondo, M.T.; M. Quinn, and M. Plebanski. 2016. Low dose cyclophosphamide: Mechanisms of T cell modulation. Cancer treatment reviews. Cancer Treat Rev., 42, 3-9.

Abdel-Hafez, S.M.; N; F. Eltahawy; R. M. Tantawi, and S. A. Abdel- Wahab.2021. Histological Study of the Damaging Effect Induced by Cyclophosphamide on Intestinal Mucosa of Adult Male Albino Rat. MJMR, Vol. 32, No. 1, pages (56-61).

Owari, M.; M. Wasa; T. Oue; S. Nose, and M.J.P.S.I Fukuzawa. 2012. Glutamine prevents intestinal mucosal injury induced by cyclophosphamide in rats. Pediatr Surg Int., 28(3):299-303.

Abdel-Hafez, S.M.N., R.A. Rifaai; W.Y. Abdelzaher. 2017. Possible protective effect of royal jelly against cyclophosphamide induced prostatic damage in male albino rats; a biochemical, histological and immunohistochemical study. Biomed Pharmacother, 90:15-23.

Shoker, R.M.H.; W. H. Al-Shammery, and S. R. Al-Aidy. A Review. 2023. Article: Free Radical and Replacement Synthetic Antioxidant by Natural Antioxidant. Journal for Research in Applied Sciences and Biotechnology. Volume-2 Issue-2 ||PP. 206-211.

Khodeer,D.M.; E. T. Mehanna; A.I. Abushouk, and M. M. Abdel-Daim. 2020. Protective Effects of Evening Primrose Oil against Cyclophosphamide-Induced Biochemical, Histopathological, and Genotoxic Alterations in Mice. Pathogens., 9(2): 98.

Ozioma, E. O. J. and O. A. N. Chinwe. 2019. Herbal medicines in African traditional medicine. Books herbal medicine. Open access peer-reviewed chapter.

Bi, X.; J. Lim, and C.J. Henry. 2017. Spices in the management of diabetes mellitus. Food Chem., 217:281-293.

Ambasta, S. K.; A. K. YAadav, and U. K. Sinha. 2017. Evaluation of anticlastogenic potential of Cinnamomum cassia bark extract against arsenic genotoxicity by using micronucleus assay in mus musculus caudal erythrocytes. Asian J Pharm Clin Res., 10 (7): 150-152.

Kumar, S.; S. Paul; Y. K. Walia; A. Kumar, and P. Singhal. 2015. Therapeutic potential of medicinal plants: A Review J Biol Chem Chron., 1(1), 46-54.

Shoker, R.M.H. 2021. Biosynthesized of silver nanoparticles by extracts from Cinnamomum cassia L. and Salvia officinalis L. in reducing the toxic effect of cyclophosphamide on some physiological and cytogenetic parameters in male albino mice. A Thesis Submitted to the College of Science, University of Baghdad, Iraq.

Kouame, K.; A. Peter; E. N. Akang; M. Adana; R. Moodley; E. C. Naidu; O. O. Azu. 2018. Effect of long-term administration of Cinnamomum cassia silver nanoparticles on organs (kidneys and liver) of Sprague-Dawley rats. Turk J Biol., 42(6): 498-505.

Al-Jassim, K.B.; A. A.H. Jawad; E. A. Al-Masoudi, and S. K. Majeed. 2016. Histopathological and biochemical effects of ivermectin on kidney functions, lungs and the ameliorative effects of vitamin C in rabbits (Lupus cuniculus). Bas J Vet Res., Vol.15,No.4.

Shoker, R.M.H.; L. M.J. Al-Shamma, and H.I.A.-B. Al-Ahmed. 2020. Role of aqueous nanoparticles and phenolic extract of Salvia officinalis L. on cyclophosphamide- induce some physiological degradation in albino mice. Plant Archives Volume 20 No. 2, pp. 5549-5555.

Gbadamosi, I. T. and A. O. Yekini. 2016. Free radical scavenging activity of different parts of Tetrapleura tetraptera (Schumach And Thorn.) Taub Bot Res Int., 9(1): 01-05

Downloads

Published

2023-09-18

How to Cite

Salman, R. J., Shoker, R. M. H., & Jebur, H. B. (2023). Review Article: Effect Anticancer Drug of Histological Alteration and Improvement their Effects by Natural Antioxidants. Journal for Research in Applied Sciences and Biotechnology, 2(4), 155–160. https://doi.org/10.55544/jrasb.2.4.22