Investigation on Anti-Ulcer Activity of Rhododendron Arboreum Flower in Wistar Rat

Authors

  • Shubhi Agarwal Research Scholar, Department of Pharmacology, Advance Institute of Biotech and Paramedical Sciences, Kanpur, Uttar Pradesh, INDIA.
  • Anurita Rajput Assistant Professor, Department of Pharmacology, Advance Institute of Biotech and Paramedical Sciences, Kanpur, Uttar Pradesh, INDIA.

DOI:

https://doi.org/10.55544/jrasb.1.5.21

Keywords:

Rhododendron arboretum, Peptic ulcers, NSAIDs, Herbal therapy, Phytochemical data

Abstract

Peptic ulcers, or open sores in the stomach or duodenum, can cause a great deal of discomfort. What's more, it affects a disproportionately significant percentage of people worldwide. Preliminary phytochemical study revealed that the Ethanol flower extract of Rhododendron arboretum (ELRA) is rich in Alkaloids, saponins, tannins, flavonoids, reducing sugars, and glycosides, all of which have been linked to poor dietary habits, prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs), stress, and infection. ELRA's significant antiulcer and wound healing actions may be due to the presence of flavonoids and saponins, as suggested by preliminary phytochemical data. This study lends credence to the long-held belief that Rhododendron arboreum flower is an excellent herbal therapy for the treatment of peptic ulcers. More conclusive research on the therapeutic efficacies of Rhododendron arboretum flower is needed, specifically regarding the plant's efficacy, protection, and in vivo toxicity. This research suggests that Rhododendron arboreum ethanol floral extract (ELRA) may be useful for the treatment of peptic ulcers.

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References

Shubhi Agarwal, & Anurita Rajput. (2022). Rhododendron Arboreum Phytochemistry, Medicinal Applications and Pharmacology: A Review. International Journal for Research in Applied Sciences and Biotechnology, 9(3), 157–165. Retrieved from https://www.ijrasb.com/index.php/ijrasb/article/view/394

Kumar, A. ., Dubey, A. ., & Singh, R. . (2022). Investigation on Anti-Ulcer Activity of Momordica dioica Fruits in Wistar Rat. International Journal for Research in Applied Sciences and Biotechnology, 9(1), 105–111. https://doi.org/10.31033/ijrasb.9.1.12.

Dubey A, Ghosh NS, Singh R. Zebrafish as An Emerging Model: An Important Testing Platform for Biomedical Science. J Pharm Negative Results 2022;13(3): 1-7. DOI: 10.47750/pnr.2022.13.03.001.

Anubhav Dubey, Raghuvendra Singh, Ashish Kumar, Gaurav Mishra, Anubha Gupta, Anuj Sonker, & Amit Mishra. (2022). A Critical Review on Changing Epidemiology of Human Monkeypox-A Current Threat with Multi-Country Outbreak. Journal of Pharmaceutical Negative Results, 660–671. Retrieved from https://www.pnrjournal.com/index.php/home/article/view/738.

Arun Kumar, Arpit Katiyar, Vijay Gautam, Rashmi Singh, & Anubhav Dubey. (2022). A Comprehensive Review on Anti-Cancer Properties of Amaranthus viridis. Journal for Research in Applied Sciences and Biotechnology, 1(3), 178–185. https://doi.org/10.55544/jrasb.1.3.23

Dubey Anubhav Ghosh Sekhar Niladry, Saxena Gyanendra Kumar, Purohit Debashis, Singh Shweta, (2022) .Management implications for neurotoxic effects associated with antibiotic use. NeuroQuantology, 6(20), 304-328. doi: 10.14704/nq.2022.20.6.NQ22034.

Dubey, A., Ghosh, N. S., Rathor, V. P. S., Patel, S., Patel, B., &Purohit, D. (2022).Sars- COV-2 infection leads to neurodegenerative or neuropsychiatric diseases. International Journal of Health Sciences, 6(S3), 2184–2197. https://doi.org/10.53730/ijhs.v6nS3.5980.

Anubhav Dubey, Yatendra Singh. Medicinal Properties of Cinchona Alkaloids - A Brief Review. Asian Journal of Research in Pharmaceutical Sciences. 2021; 11(3):224-8. doi: 10.52711/2231-5659.2021.00036

Yadav, K., Sachan, A., Kumar, S., & Dubey, A. (2022). Techniques For Increasing Solubility: A Review Of Conventional And New Strategies. Asian Journal of Pharmaceutical Research and Development, 10(2), 144-153.

Dubey Anubhav, Tiwari Mamta, Kumar Vikas, Srivastava, Kshama, Singh, Akanksha. Investigation of Anti-Hyperlipidemic Activity of Vinpocetine in Wistar Rat.International Journal of Pharmaceutical Research 2020; 12(02):1879-1882. DOI: https://doi.org/10.31838/ijpr/2020.12.02.250.

Akshay Tiwari, Shalini Singh, Anubhav Dubey and Yatendra Singh. “A preliminary study on anti-hyperlipidemic activity of cinnamon oil in wistar rat”, 2021. International Journal of Current Research, 13, (03), 16741-16745.

Dubey Anubhav, Tiwari M, Singh Yatendra, Kumar N, Srivastava K. Investigation of anti-Pyretic activity of vinpocetine in wistar rat, International Journal of Pharmaceutical Research 2020;12(2):1901-1906. DOI: https://doi.org/10.31838/ijpr/2020.12.02.254.

Raj Pratap Singh, Dr. Vishal Dubey, Anubhav Dubey & Dr. Shantanu, Liposomal gels for vaginal drug delivery of Amoxicillin Trihydrate, International Journal of Medical Research and Pharmaceutical Sciences;2020 7(8) 1-13.

Gaurava Srivastav, Dakshina Gupta, Anubhav Dubey, & Neeraj Kumar. (2022). Investigation of Anti- Pyretic Activity of Cinnamon Oil in Wistar Rat. Journal for Research in Applied Sciences and Biotechnology, 1(3), 51–56. https://doi.org/10.55544/jrasb.1.3.7

Kumar, N., Dubey, A., Mishra, A., & Tiwari, P. (2020). Ethosomes: A Novel Approach in Transdermal Drug Delivery System. International Journal of Pharmacy & Life Sciences, 11(5).

Srivastava Kshama, Dubey Anubhav, Tiwari Mamta, Dubey Anurag, To evaluate the synergistic effect of pinitol with glimepride in diabetic wistar rats;7,(13)2020, 2058-2062.

Dubey A., Kumar R., Kumar S., Kumar N., Mishra A., Singh Y. and Tiwari M. (2020). Review on Vinpocetine, Int. J. of Pharm. & Life Sci., 11(5): 6590-6597.

Srivastava K., Tiwari M., Dubey A. and Dwivedi A. (2020). D-Pinitol - A Natural Phytomolecule and its Pharmacological effect, Int. J. of Pharm. & Life Sci., 11(5): 6609-6623.

Dubey, A., Tiwari, D., Singh, Y., & Prakash, O. (2021). PankajSingh. Drug repurposing in Oncology: Opportunities and challenges. Int J of Allied Med Sci and Clin Res, 9(1), 68-87.

Meher, C. P., Purohit, D., Kumar, A., Singh, R., & Dubey, A. (2022). An updated review on morpholine derivatives with their pharmacological actions. International Journal of Health Sciences, 6(S3), 2218–2249. https://doi.org/10.53730/ijhs.v6nS3.5983.

Patnaik, S., Purohit, D., Biswasroy, P., Diab, W. M., & Dubey, A. (2022). Recent advances for commedonal acne treatment by employing lipid nanocarriers topically. International Journal of Health Sciences, 6(S8), 180–205. https://doi.org/10.53730/ijhs.v6nS8.9671

Anubhav Dubey, Deepanshi Tiwari, Kshama Srivastava, Om Prakash and Rohit Kushwaha. A discussion on vinca plant. J Pharmacogn Phytochem 2020;9(5):27-31.

Rasheed Khushnuma, Gupta Dakshina, Dubey Anubhav, Singh Yatendra, A REVIEW ON β-ESCIN, Indian Journal of Medical Research and Pharmaceutical Sciences, 2021;8(1),10-16. DOI: https://doi.org/10.29121/ijmrps.v8.i1.2020.2.

Dubey Anubhav, Kumar Abhay, Peeyush, Singh Jitendra, Medicinal property of Callistemon viminalis, International Journal of Pharmacognosy and Life Science 2021; 2(2): 15-20. DOI: https://doi.org/10.33545/27072827.2021.v2.i2a.35.

Dubey, Anubhav, Niladry Sekhar Ghosh, Nidhee Agnihotri and Amit Kumar et al. “Herbs Derived Bioactive Compounds and their Potential for the Treatment of Neurological Disorders.” Clin Schizophr Relat Psychoses 16 (2022). Doi: 10.3371/CSRP.DANG.081922

Yadav Priyanka, Dubey Anubhav, Formulation and characterization of anti-epileptic drug transdermal patch for enhance skin permeation, European Journal of Biomedical and Pharmaceutical Sciences 2021: 8, (9), 784-790. http://www.ejbps.com.

Prerna, Dubey Anubhav, Gupta Ratan, Nanoparticles: An Overview, Drugs and Cell Therapies in Haematology2021;10(1),1487-1497.

Panda Braja Bihari, Patnaas,Swastik, Purohit Debashish,Das Shubhashree, Dubey Anubhav, Impact of sodium starch glycolate on Physico-chemical characteristics of mouth dissolving film of Fexofenadine, NeuroQuantology2022 ; 20 (6)7604-7613.doi: 10.14704/nq.2022.20.6.NQ22759.

Anubhav Dubey, Deepanshi Tiwari, Kshama Srivastava, Om Prakash and Rohit Kushwaha. A discussion on vinca plant. J Pharmacogn Phytochem 2020;9(5):27-31.

Dubey, Anubhav, Niladry Sekhar Ghosh, Nidhee Agnihotri and Amit Kumar et al. “Herbs Derived Bioactive Compounds and their Potential for the Treatment of Neurological Disorders.” Clin Schizophr Relat Psychoses 16 (2022). Doi: 10.3371/CSRP.DANG.081922.

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Published

2023-01-13

How to Cite

Agarwal, S., & Rajput, A. (2023). Investigation on Anti-Ulcer Activity of Rhododendron Arboreum Flower in Wistar Rat. Journal for Research in Applied Sciences and Biotechnology, 1(5), 195–201. https://doi.org/10.55544/jrasb.1.5.21

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