Role of Herbal Essential Oil in Cervical Cancer: A Systematic Review

Shailendra Sah; Roshan Kumar; Rita Saini; Shivanand M. Patil

doi:10.55544/jrasb.3.5.10

Authors

Shailendra Sah Research Scholar, Department of Pharmacy, Shree Dev Bhoomi Institute of Education Science and Technology (SDBIT), Dehradun, INDIA.
Roshan Kumar Assistant Professor, Department of Pharmacy, Shree Dev Bhoomi Institute of Education Science and Technology (SDBIT), Dehradun, INDIA.
Rita Saini Associate Professor, Department of Pharmacy, Shree Dev Bhoomi Institute of Education Science and Technology (SDBIT), Dehradun, INDIA.
Shivanand M. Patil Professor, Department of Pharmacy, Shree Dev Bhoomi Institute of Education Science and Technology (SDBIT), Dehradun, INDIA.

DOI:

https://doi.org/10.55544/jrasb.3.5.10

Keywords:

essential oil, natural product, phytomedicine, cancer, drug delivery, nanoparticle

Abstract

Cancer of the cervix is a disease that is ubiquitous and frequently severe, and it affects women all over the world. Conventional treatment methods, which include surgical procedures, chemotherapy, and radiation therapy, have been shown to dramatically enhance survival rates; nevertheless, these methods are frequently accompanied with adverse effects and difficulties that might have an influence on the quality of life of a patient. In recent years, there has been a growing interest in the utilisation of essential oils in the cancer treatment and management of cervical cancer. This review offers a comprehensive investigation into the function that various essential oils play in the development of cervical cancer. It also includes insights into the possible advantages of these oils as well as the body of research that has been conducted on them. Additionally, the analysis dives into the future directions and issues that will be faced in this developing industry, with a particular focus on advancements in delivery methods and interesting research areas. For the purpose of enhancing the anticancer qualities of essential oils, the encapsulation of essential oils with solid lipid nanoparticles, the nanoemulsification of essential oils, or the combining of essential oils with conventional treatments have all demonstrated promising results. This review attempts to provide a comprehensive viewpoint, balancing the potential of these natural therapies with the obstacles and issues that need to be addressed. As the employment of essential oils in the treatment or management of cervical cancer continues to develop, this study will attempt to provide a comprehensive perspective. The study will attempt to strike a balance between the potential of these natural treatments and the obstacles and issues that need to be addressed.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Hui, D., & Bruera, E. (2017). The Edmonton Symptom Assessment System 25 years later: past, present, and future developments. Journal of pain and symptom management, 53(3), 630-643

Berger, A. M., Mooney, K., Alvarez-Perez, A., Breitbart, W. S., Carpenter, K. M., Cella, D., ... & Smith, C. (2015). Cancer-related fatigue, version 2.2015. Journal of the National Comprehensive Cancer Network, 13(8), 1012-1039

Cormie, P., Zopf, E. M., Zhang, X., & Schmitz, K. H. (2017). The impact of exercise on cancer mortality, recurrence, and treatment-related adverse effects. Epidemiologic reviews, 39(1), 71-92.

Hayes, S. C., Spence, R. R., Galvão, D. A., & Newton, R. U. (2023). The Exercise and Sports Science Australia position statement: exercise medicine in cancer management. Pensar en Movimiento: Revista de ciencias del ejercicio y la salud, 21(2).

Zhang, X., Qiu, H., Li, C., Cai, P., & Qi, F. (2021). The positive role of traditional Chinese medicine as an adjunctive therapy for cancer. Bioscience trends, 15(5), 283-298.

Kang, Y. E., Yoon, J. H., Park, N. H., Ahn, Y. C., Lee, E. J., & Son, C. G. (2023). Prevalence of cancer-related fatigue based on severity: a systematic review and meta-analysis. Scientific reports, 13(1), 12815.

Chayadi, E., Baes, N., & Kiropoulos, L. (2022). The effects of mindfulness-based interventions on symptoms of depression, anxiety, and cancer-related fatigue in oncology patients: A systematic review and meta-analysis. PloS one, 17(7), e0269519.

Schmidt, M. E., Wiskemann, J., & Steindorf, K. (2018). Quality of life, problems, and needs of disease-free breast cancer survivors 5 years after diagnosis. Quality of Life Research, 27, 2077-2086.

Narayanasamy, R. K., Muthusekar, R. M., Nagalingam, S. P., Thyagarajan, S., Ramakrishnan, B., & Perumal, K. (2021). Lower pretreatment hemoglobin status and treatment breaks in locally advanced head and neck squamous cell carcinoma during concurrent chemoradiation. Indian journal of cancer, 58(1), 62-68.

Frikkel, J., Götte, M., Beckmann, M., Kasper, S., Hense, J., Teufel, M., ... & Tewes, M. (2020). Fatigue, barriers to physical activity and predictors for motivation to exercise in advanced Cancer patients. BMC palliative care, 19, 1-11.

Nakano, J., Hashizume, K., Fukushima, T., Ueno, K., Matsuura, E., Ikio, Y., ... & Kusuba, Y. (2018). Effects of aerobic and resistance exercises on physical symptoms in cancer patients: a meta-analysis. Integrative cancer therapies, 17(4), 1048-1058.

Haskell, C. M., & Berek, J. S. (1980). Cancer treatment. (No Title).

Bodden, W. L. (1991). U.S. Patent No. 5,069,662. Washington, DC: U.S. Patent and Trademark Office.

Edwards, S. D., Baker, J., Strul, B., & Lax, R. G. (1997). U.S. Patent No. 5,599,345. Washington, DC: U.S. Patent and Trademark Office.

Gough, E. J., & Stein, A. A. (1997). U.S. Patent No. 5,672,174. Washington, DC: U.S. Patent and Trademark Office.

Van den Beuken-van Everdingen, M. H. J., De Rijke, J. M., Kessels, A. G., Schouten, H. C., Van Kleef, M., & Patijn, J. (2007). Prevalence of pain in patients with cancer: a systematic review of the past 40 years. Annals of oncology, 18(9), 1437-1449

Van Den Beuken-Van, M. H., Hochstenbach, L. M., Joosten, E. A., Tjan-Heijnen, V. C., & Janssen, D. J. (2016). Update on prevalence of pain in patients with cancer: systematic review and meta-analysis. Journal of pain and symptom management, 51(6), 1070-1090.

Gold, S. M., Köhler-Forsberg, O., Moss-Morris, R., Mehnert, A., Miranda, J. J., Bullinger, M., ... & Otte, C. (2020). Comorbid depression in medical diseases. Nature Reviews Disease Primers, 6(1), 69.

Emery, J., Butow, P., Lai-Kwon, J., Nekhlyudov, L., Rynderman, M., & Jefford, M. (2022). Management of common clinical problems experienced by survivors of cancer. The Lancet, 399(10334), 1537-1550.

He, Y., Guo, X., May, B. H., Zhang, A. L., Liu, Y., Lu, C., ... & Zhang, H. (2020). Clinical evidence for association of acupuncture and acupressure with improved cancer pain: a systematic review and meta-analysis. JAMA oncology, 6(2), 271-278.

Kaasa, S., Loge, J. H., Aapro, M., Albreht, T., Anderson, R., Bruera, E., ... & Lundeby, T. (2018). Integration of oncology and palliative care: a Lancet Oncology Commission. The lancet oncology, 19(11), e588-e653.

Paice, J. A., Bohlke, K., Barton, D., Craig, D. S., El-Jawahri, A., Hershman, D. L., ... & Bruera, E. (2023). Use of opioids for adults with pain from cancer or cancer treatment: ASCO guideline. Journal of Clinical Oncology, 41(4), 914-930.

Corasaniti, M. T., Bagetta, G., Morrone, L. A., Tonin, P., Hamamura, K., Hayashi, T., ... & Scuteri, D. (2023). Efficacy of essential oils in relieving cancer pain: a systematic review and meta-analysis. International journal of molecular sciences, 24(8), 7085.

Meyer, C., Brockmueller, A., Buhrmann, C., & Shakibaei, M. (2024). Prevention and Co-management of breast cancer-related osteoporosis using resveratrol. Nutrients, 16(5), 708.

Hartup, S., & Briggs, M. (2024). Managing chronic pain after breast cancer treatments: are web-based interventions the future?. Current Opinion in Supportive and Palliative Care, 18(1), 47-54.

Meyer, C., Brockmueller, A., Buhrmann, C., & Shakibaei, M. (2024). Prevention and Co-Management of Breast Cancer-Related Osteoporosis Using Resveratrol. Nutrients 2024, 16, 708.

Liang, X., Zhou, W., & Fan, Y. (2021). Erector spinae plane block for spinal surgery: a systematic review and meta-analysis. The Korean Journal of Pain, 34(4), 487-500.

van den Broek, R. J., van de Geer, R., Schepel, N. C., Liu, W. Y., Bouwman, R. A., & Versyck, B. (2021). Evaluation of adding the Erector spinae plane block to standard anesthetic care in patients undergoing posterior lumbar interbody fusion surgery. Scientific Reports, 11(1), 7631.

Tantri, A. R., Rahmi, R., Marsaban, A. H. M., Satoto, D., Rahyussalim, A. J., & Sukmono, R. B. (2023). Comparison of postoperative IL-6 and IL-10 levels following Erector Spinae Plane Block (ESPB) and classical Thoracolumbar Interfascial Plane (TLIP) block in a posterior lumbar decompression and stabilization procedure: a randomized controlled trial. BMC anesthesiology, 23(1), 13.

Wetmore, D. S., Dalal, S., Shinn, D., Shahi, P., Vaishnav, A., Chandra, A., ... & Qureshi, S. A. (2024). Erector spinae plane block reduces immediate postoperative pain and opioid demand after minimally invasive transforaminal lumbar interbody fusion. Spine, 49(1), 7-14.

Patel, A. A., Walker, C. T., Prendergast, V., Radosevich, J. J., Grimm, D., Godzik, J., ... & Turner, J. D. (2020). Patient-controlled analgesia following lumbar spinal fusion surgery is associated with increased opioid consumption and opioid-related adverse events. Neurosurgery, 87(3), 592-601.

Wahdan, A. S., Radwan, T. A., Mohammed, M. M., Abdalla Mohamed, A., & Salama, A. K. (2021). Effect of bilateral ultrasound-guided erector spinae blocks on postoperative pain and opioid use after lumbar spine surgery: a prospective randomized controlled trial. Egyptian Journal of Anaesthesia, 37(1), 100-106.

Fallon, M., Giusti, R., Aielli, F., Hoskin, P., Rolke, R., Sharma, M., & Ripamonti, C. I. (2018). Management of cancer pain in adult patients: ESMO Clinical Practice Guidelines. Annals of Oncology, 29, iv166-iv191.

da Costa, R., Passos, G. F., Quintão, N. L., Fernandes, E. S., Maia, J. R. L., Campos, M. M., & Calixto, J. B. (2020). Taxane‐induced neurotoxicity: Pathophysiology and therapeutic perspectives. British journal of pharmacology, 177(14), 3127-3146.

Yang, Y., Zhao, B., Gao, X., Sun, J., Ye, J., Li, J., & Cao, P. (2021). Targeting strategies for oxaliplatin-induced peripheral neuropathy: clinical syndrome, molecular basis, and drug development. Journal of experimental & clinical cancer research, 40, 1-25.

Cavaletti, G., & Marmiroli, P. (2020). Management of oxaliplatin-induced peripheral sensory neuropathy. Cancers, 12(6), 1370.

Gérard, A., Woolfe, A., Mottet, G., Reichen, M., Castrillon, C., Menrath, V., ... & Brenan, C. (2020). High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics. Nature biotechnology, 38(6), 715-721.

Awuchi, C. G., Amagwula, I. O., Priya, P., Kumar, R., Yezdani, U., & Khan, M. G. (2020). Aflatoxins in foods and feeds: A review on health implications, detection, and control. Bull. Environ. Pharmacol. Life Sci, 9, 149-155.

Kaur, R. P., Vasudeva, K., Kumar, R., & Munshi, A. (2018). Role of p53 gene in breast cancer: focus on mutation spectrum and therapeutic strategies. Current pharmaceutical design, 24(30), 3566-3575.

Kumar, R., Saha, P., Kumar, Y., Sahana, S., Dubey, A., & Prakash, O. (2020). A review on diabetes mellitus: type1 & Type2. World Journal of Pharmacy and Pharmaceutical Sciences, 9(10), 838-850.

Kumar, R., Sood, U., Gupta, V., Singh, M., Scaria, J., & Lal, R. (2020). Recent advancements in the development of modern probiotics for restoring human gut microbiome dysbiosis. Indian journal of microbiology, 60, 12-25.

Daharia, A., Jaiswal, V. K., Royal, K. P., Sharma, H., Joginath, A. K., Kumar, R., & Saha, P. (2022). A Comparative review on ginger and garlic with their pharmacological Action. Asian Journal of Pharmaceutical Research and Development, 10(3), 65-69.

Kumar, R., Saha, P., Lokare, P., Datta, K., Selvakumar, P., & Chourasia, A. (2022). A systemic review of Ocimum sanctum (Tulsi): Morphological characteristics, phytoconstituents and therapeutic applications. International Journal for Research in Applied Sciences and Biotechnology, 9(2), 221-226.

Daharia, A., Jaiswal, V. K., Royal, K. P., Sharma, H., Joginath, A. K., Kumar, R., & Saha, P. (2022). A Comparative review on ginger and garlic with their pharmacological Action. Asian Journal of Pharmaceutical Research and Development, 10(3), 65-69.

Kumar, R., & Saha, P. (2022). A review on artificial intelligence and machine learning to improve cancer management and drug discovery. International Journal for Research in Applied Sciences and Biotechnology, 9(3), 149-156.

Saha, P., Nyarko, R. O., Lokare, P., Kahwa, I., Boateng, P. O., & Asum, C. (2022). Effect of Covid-19 in Management of Lung Cancer Disease: A Review. Asian Journal of Pharmaceutical Research and Development, 10(3), 58-64.

Amle, V. S., Rathod, D. A., Keshamma, E., Kumar, V., Kumar, R., & Saha, P. (2022). Bioactive herbal medicine use for eye sight: a meta analysis. Journal for Research in Applied Sciences and Biotechnology, 1(3), 42-50.

Singh, Y., Paswan, S. K., Kumar, R., Otia, M. K., Acharya, S., Kumar, D., & Keshamma, E. (2022). Plant & Its Derivative Shows Therapeutic Activity on Neuroprotective Effect. Journal for Research in Applied Sciences and Biotechnology, 1(2), 10-24.

Keshamma, E., Paswan, S. K., Kumar, R., Saha, P., Trivedi, U., Chourasia, A., & Otia, M. (2022). Alkaloid Based Chemical Constituents of Ocimum santum & Cinchona Bark: A Meta Analysis. Journal for Research in Applied Sciences and Biotechnology, 1(2), 35-42.

Nyarko, R. O., Roopini, R., Raviteja, V., Awuchi, C. G., Kumar, R., Faller, E. M., ... & Saha, P. (2022). Novel Sars-CoV-2 Variants & Therapeutic Effects. Journal for Research in Applied Sciences and Biotechnology, 1(2), 25-34.

Kumar, R., Saha, P., Keshamma, E., Sachitanadam, P., & Subramanian, M. (2022). Docking studies of some novel Hetrocyclic compound as Acat inhibitors: A meta analysis. Journal for Research in Applied Sciences and Biotechnology, 1(3), 33-41.

Awuchi, C. G., Saha, P., Amle, V. S., Nyarko, R. O., Kumar, R., Boateng, E. A., ... & Asum, C. (2023). A Study of various medicinal plants used in ulcer treatment: A review. Journal for Research in Applied Sciences and Biotechnology, 2(1), 234-246.

Sultana, A., Singh, M., Kumar, A., Kumar, R., Saha, P., Kumar, R. S., & Kumar, D. (2022). To identify drug-drug interaction in cardiac patients in tertiary care hospitals. Journal for Research in Applied Sciences and Biotechnology, 1(3), 146-152.

Kashyap, N., Kumar, R., Rana, V., Sood, P., & Chauhan, T. (2023). Role of Terpenoids Active Ingredients Targeting for Neuroprotective Agents. Journal for Research in Applied Sciences and Biotechnology, 2(3), 22-40.

Nyarko, R. O., Awuchi, C. G., Kumar, R., Boateng, E., Kahwa, I., Boateng, P. O., ... & Saha, P. (2022). Evaluation of cafeteria diet in experimental animal with plant extract of calotropis procera for obesity parameter. Journal for Research in Applied Sciences and Biotechnology, 1(3), 107-113.

Butola, K., Bisht, V., & Kumar, R. (2023). Recent Approaches of Ocular Disease and Its Herbal Product Treatment: An Updates. Journal for Research in Applied Sciences and Biotechnology, 2(2), 102-114.

Kohli, A., & Kumar, R. (2023). Role of Antioxidants of Natural Herbs in Management of Male Infertility. Journal for Research in Applied Sciences and Biotechnology, 2(1), 55-80.

Subramanian, M., Keshamma, E., Janjua, D., Kumar, D., Kumar, R., Saha, P., ... & Rao, S. (2022). Quality risk management approach for drug development and its future prospectives. Journal for Research in Applied Sciences and Biotechnology, 1(3), 166-177.

Patel, R. K., Gangwar, D., Gupta, H., Sharma, N., & Kumar, R. (2023). Plants Alkaloids Based Compound as Therapeutic Potential for Neurodegenerative. Journal for Research in Applied Sciences and Biotechnology, 2(2), 14-26.

Kumar, A., Uniyal, Y., & Kumar, R. (2022). Recent Advancement of Colorectal Cancer and Their Herbal Essential Oil Treatment. Journal for Research in Applied Sciences and Biotechnology, 1(5), 133-144.

Kumar, V., Gupta, H., & Kumar, R. (2024). Therapeutic Approaches of Nutraceuticals in Neurological Disorders: A Review. Journal for Research in Applied Sciences and Biotechnology, 3(2), 261-281.

Kumar, R. (2023). Investigation of In-Vitro Method of Antiulcer Activity. Journal for Research in Applied Sciences and Biotechnology, 2(1), 264-267.

Nyarko, R. O., Awuchi, C. G., Kumar, R., Boateng, E., Kahwa, I., Boateng, P. O., ... & Saha, P. (2022). Effect of Calotropis Procera Extract on Appetitte, Body Weight & Lipid Profile in Cafeteria Diet Induced Obesity in Experimental Animal. Journal for Research in Applied Sciences and Biotechnology, 1(3), 107-113.

Sahana, S., Kumar, R., Nag, S., Paul, R., Chatterjee, I., & Guha, N. (2020). A Review On Alzheimer Disease And Future Prospects.

Nyarko, R. O., Kumar, R., Sharma, S., Chourasia, A., Roy, A., & Saha, P. (2022). Antibacterial Activity of Herbal Plant-Tinospora Cordifolia And Catharnthus Roseus.

Keshamma, E., Paswan, S. K., Kumar, R., Saha, P., Trivedi, U., Chourasia, A., & Otia, M. (2022). Alkaloid Based Chemical Constituents of Ocimum santum & Cinchona Bark: A Meta Analysis. Journal for Research in Applied Sciences and Biotechnology, 1(2), 35-42.

Saini, R., & Juyal, D. (2018). Sapindus mukorossi: A review article. The Pharma Innovation, 7(5, Part G), 470.

Patil, S. M., & Saini, R. (2012). Anticonvulsant activity of methanolic extract of Jasminum grandflorum Linn in experimental animals.

Kishore, L. (2021). Chapter-7 Clinical Evaluation of Diabetic Complication: Nephropathy. PHARMACEUTICAL SCIENCES, 113.

Mehendiratta, H., Singh, S., Sharma, N., Kishore, L., Dwivedi, M., & Rani, A. (2024). Advances in Liposomes-Based-Therapeutics as Cutting-Edge for Ocular Fungal Infections: An Updated Review. BioNanoScience, 1-14.

Saha, P., Kumar, R., Nyarko, R. O., Kahwa, I., & Owusu, P. (2021). Herbal Secondary Metabolite For Gastro-Protective Ulcer Activity With Api Structures.

Maney, V., & Singh, M. (2019). The synergism of platinum-gold bimetallic Nanoconjugates enhances 5-fluorouracil delivery in vitro. Pharmaceutics, 11(9), 439.

Eivazzadeh-Keihan, R., Noruzi, E. B., Chidar, E., Jafari, M., Davoodi, F., Kashtiaray, A., ... & Mahdavi, M. (2022). Applications of carbon-based conductive nanomaterials in biosensors. Chemical Engineering Journal, 442, 136183.

Ni, Y., Ouyang, H., Yu, L., Ling, C., Zhu, Z., He, A., & Liu, R. (2022). Label-free electrochemical aptasensor based on magnetic α-Fe2O3/Fe3O4 heterogeneous hollow nanorods for the detection of cancer antigen 125. Bioelectrochemistry, 148, 108255.

Chavda, V. P., Balar, P. C., & Patel, S. B. (2023). Interventional nanotheranostics in hepatocellular carcinoma. Nanotheranostics, 7(2), 128.

Liu, C., Lin, R., Lai, H., Pi, F., Xue, Q., Chen, T., & He, W. (2023). Thermosensitive selenium hydrogel boosts antitumor immune response for hepatocellular carcinoma chemoradiotherapy. Nano Today, 50, 101823.

Crintea, A., Dutu, A. G., Sovrea, A., Constantin, A. M., Samasca, G., Masalar, A. L., ... & Craciun, A. M. (2022). Nanocarriers for drug delivery: an overview with emphasis on vitamin D and K transportation. Nanomaterials, 12(8), 1376.

Bakrania, A., To, J., Zheng, G., & Bhat, M. (2023). Targeting Wnt-β-catenin signaling pathway for HCC nanomedicine. Gastro Hep Advances.

Periasamy, V. S., Athinarayanan, J., & Alshatwi, A. A. (2016). Anticancer activity of an ultrasonic nanoemulsion formulation of Nigella sativa L. essential oil on human breast cancer cells. Ultrasonics sonochemistry, 31, 449-455.

Ribeiro-Santos, R., Andrade, M., de Melo, N. R., & Sanches-Silva, A. (2017). Use of essential oils in active food packaging: Recent advances and future trends. Trends in food science & technology, 61, 132-140.

Sharma, M., Grewal, K., Jandrotia, R., Batish, D. R., Singh, H. P., & Kohli, R. K. (2022). Essential oils as anticancer agents: Potential role in malignancies, drug delivery mechanisms, and immune system enhancement. Biomedicine & Pharmacotherapy, 146, 112514.

Blowman, K., Magalhães, M., Lemos, M. F. L., Cabral, C., & Pires, I. M. (2018). Anticancer properties of essential oils and other natural products. Evidence‐Based Complementary and Alternative Medicine, 2018(1), 3149362.

Sharifi-Rad, J., Ozleyen, A., Boyunegmez Tumer, T., Oluwaseun Adetunji, C., El Omari, N., Balahbib, A., ... & C. Cho, W. (2019). Natural products and synthetic analogs as a source of antitumor drugs. Biomolecules, 9(11), 679.

Yammine, J., Chihib, N. E., Gharsallaoui, A., Ismail, A., & Karam, L. (2024). Advances in essential oils encapsulation: Development, characterization and release mechanisms. Polymer Bulletin, 81(5), 3837-3882.

Khan, I., Bahuguna, A., Kumar, P., Bajpai, V. K., & Kang, S. C. (2018). In vitro and in vivo antitumor potential of carvacrol nanoemulsion against human lung adenocarcinoma A549 cells via mitochondrial mediated apoptosis. Scientific reports, 8(1), 144.

Yao, C., Zhao, S., Liu, L., Liu, Z., & Chen, G. (2022). Ultrasonic emulsification: basic characteristics, cavitation, mechanism, devices and application. Frontiers of Chemical Science and Engineering, 16(11), 1560-1583.

Pereira dos Santos, E., Nicácio, P. H. M., Coêlho Barbosa, F., Nunes da Silva, H., Andrade, A. L. S., Lia Fook, M. V., ... & Farias Leite, I. (2019). Chitosan/essential oils formulations for potential use as wound dressing: Physical and antimicrobial properties. Materials, 12(14), 2223.

Alves-Silva, J. M., Romane, A., Efferth, T., & Salgueiro, L. (2017). North African medicinal plants traditionally used in cancer therapy. Frontiers in pharmacology, 8, 383.

Amrati, F. E. Z., Bourhia, M., Slighoua, M., Salamatullah, A. M., Alzahrani, A., Ullah, R., ... & Bousta, D. (2021). Traditional medicinal knowledge of plants used for cancer treatment by communities of mountainous areas of Fez-Meknes-Morocco. Saudi Pharmaceutical Journal, 29(10), 1185-1204.

Kalaj, M., Bentz, K. C., Ayala Jr, S., Palomba, J. M., Barcus, K. S., Katayama, Y., & Cohen, S. M. (2020). MOF-polymer hybrid materials: from simple composites to tailored architectures. Chemical reviews, 120(16), 8267-8302.

Dechnik, J., Gascon, J., Doonan, C. J., Janiak, C., & Sumby, C. J. (2017). Mixed‐matrix membranes. Angewandte Chemie International Edition, 56(32), 9292-9310.

He, S., Zhu, B., Jiang, X., Han, G., Li, S., Lau, C. H., ... & Shao, L. (2022). Symbiosis-inspired de novo synthesis of ultrahigh MOF growth mixed matrix membranes for sustainable carbon capture. Proceedings of the National Academy of Sciences, 119(1), e2114964119.

Lee, T. H., Lee, B. K., Yoo, S. Y., Lee, H., Wu, W. N., Smith, Z. P., & Park, H. B. (2023). PolyMOF nanoparticles constructed from intrinsically microporous polymer ligand towards scalable composite membranes for CO2 separation. Nature Communications, 14(1), 8330.

Ahmadijokani, F., Molavi, H., Ahmadipouya, S., Rezakazemi, M., Ghaffarkhah, A., Kamkar, M., ... & Arjmand, M. (2023). Polyurethane-based membranes for CO2 separation: A comprehensive review. Progress in Energy and Combustion Science, 97, 101095.

Al-Rowaili, F. N., Khaled, M., Jamal, A., & Zahid, U. (2023). Mixed matrix membranes for H2/CO2 gas separation-a critical review. Fuel, 333, 126285.

Semino, R., Moreton, J. C., Ramsahye, N. A., Cohen, S. M., & Maurin, G. (2018). Understanding the origins of metal–organic framework/polymer compatibility. Chemical science, 9(2), 315-324.

Sutrisna, P. D., Hou, J., Zulkifli, M. Y., Li, H., Zhang, Y., Liang, W., ... & Chen, V. (2018). Surface functionalized UiO-66/Pebax-based ultrathin composite hollow fiber gas separation membranes. Journal of Materials Chemistry A, 6(3), 918-931.

Saini, N., & Awasthi, K. (2022). Insights into the progress of polymeric nano-composite membranes for hydrogen separation and purification in the direction of sustainable energy resources. Separation and Purification Technology, 282, 120029.

Wang, Y., Ren, Y., Wu, H., Wu, X., Yang, H., Yang, L., ... & Jiang, Z. (2020). Amino-functionalized ZIF-7 embedded polymers of intrinsic microporosity membrane with enhanced selectivity for biogas upgrading. Journal of Membrane Science, 602, 117970.

Ma, L., Svec, F., Lv, Y., & Tan, T. (2019). Engineering of the filler/polymer interface in metal–organic framework‐based mixed‐matrix membranes to enhance gas separation. Chemistry–An Asian Journal, 14(20), 3502-3514.

Zhang, Q., Li, S., Wang, C., Chang, H. C., & Guo, R. (2020). Carbon nanotube-based mixed-matrix membranes with supramolecularly engineered interface for enhanced gas separation performance. Journal of Membrane Science, 598, 117794.

Lv, X., Huang, L., Ding, S., Wang, J., Li, L., Liang, C., & Li, X. (2021). Mixed matrix membranes comprising dual-facilitated bio-inspired filler for enhancing CO2 separation. Separation and Purification Technology, 276, 119347.

Zhou, H., Akram, A., Semiao, A. J., Malpass-Evans, R., Lau, C. H., McKeown, N. B., & Zhang, W. (2022). Enhancement of performance and stability of thin-film nanocomposite membranes for organic solvent nanofiltration using hypercrosslinked polymer additives. Journal of Membrane Science, 644, 120172.

Lee, J., Satheeshkumar, C., Yu, H. J., Kim, S., Lee, J. S., Seo, M., & Kim, M. (2020). Pore engineering of covalently connected metal–organic framework nanoparticle–mixed-matrix membrane composites for molecular separation. ACS Applied Nano Materials, 3(9), 9356-9362.

Arbyn, M., Weiderpass, E., Bruni, L., de Sanjosé, S., Saraiya, M., Ferlay, J., & Bray, F. (2020). Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. The Lancet Global Health, 8(2), e191-e203.

Singh, D., Vignat, J., Lorenzoni, V., Eslahi, M., Ginsburg, O., Lauby-Secretan, B., ... & Vaccarella, S. (2023). Global estimates of incidence and mortality of cervical cancer in 2020: a baseline analysis of the WHO Global Cervical Cancer Elimination Initiative. The lancet global health, 11(2), e197-e206.

Stelzle, D., Tanaka, L. F., Lee, K. K., Khalil, A. I., Baussano, I., Shah, A. S., ... & Dalal, S. (2021). Estimates of the global burden of cervical cancer associated with HIV. The lancet global health, 9(2), e161-e169.

Buskwofie, A., David-West, G., & Clare, C. A. (2020). A review of cervical cancer: incidence and disparities. Journal of the National Medical Association, 112(2), 229-232.

Yang, N., Cao, C., Lv, X., Zhang, T., Shao, J., Song, X., ... & Dong, X. (2023). Photo‐facilitated chemodynamic therapeutic agents: Synthesis, mechanisms, and biomedical applications. BMEMat, 1(1), e12005.

Colzani, E., Johansen, K., Johnson, H., & Celentano, L. P. (2021). Human papillomavirus vaccination in the European Union/European Economic Area and globally: a moral dilemma. Eurosurveillance, 26(50), 2001659.

Burmeister, C. A., Khan, S. F., Schäfer, G., Mbatani, N., Adams, T., Moodley, J., & Prince, S. (2022). Cervical cancer therapies: Current challenges and future perspectives. Tumour Virus Research, 13, 200238.

Arbyn, M., Weiderpass, E., Bruni, L., de Sanjosé, S., Saraiya, M., Ferlay, J., & Bray, F. (2020). Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. The Lancet Global Health, 8(2), e191-e203.

Arbyn, M., Weiderpass, E., Bruni, L., de Sanjosé, S., Saraiya, M., Ferlay, J., & Bray, F. (2019). Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. The Lancet. Global Health, 8(2), e191-e203.

Johnson, C. A., James, D., Marzan, A., & Armaos, M. (2019, April). Cervical cancer: an overview of pathophysiology and management. In Seminars in oncology nursing (Vol. 35, No. 2, pp. 166-174). WB Saunders.

De Sanjosé, S., Diaz, M., Castellsagué, X., Clifford, G., Bruni, L., Muñoz, N., & Bosch, F. X. (2007). Worldwide prevalence and genotype distribution of cervical human papillomavirus DNA in women with normal cytology: a meta-analysis. The Lancet infectious diseases, 7(7), 453-459.

Torre, L. A., Islami, F., Siegel, R. L., Ward, E. M., & Jemal, A. (2017). Global cancer in women: burden and trends. Cancer epidemiology, biomarkers & prevention, 26(4), 444-457.

Bruni, L., Diaz, M., Castellsagué, M., Ferrer, E., Bosch, F. X., & de Sanjosé, S. (2010). Cervical human papillomavirus prevalence in 5 continents: meta-analysis of 1 million women with normal cytological findings. Journal of Infectious Diseases, 202(12), 1789-1799.

Fang, Y., Tian, S., Pan, Y., Li, W., Wang, Q., Tang, Y., ... & Shu, Y. (2020). Pyroptosis: A new frontier in cancer. Biomedicine & Pharmacotherapy, 121, 109595.

Moodley, J. R., Hoffman, M., Carrara, H., Allan, B. R., Cooper, D. D., Rosenberg, L., ... & Williamson, A. L. (2006). HIV and pre-neoplastic and neoplastic lesions of the cervix in South Africa: a case-control study. BMC cancer, 6, 1-6.

Finocchario-Kessler, S., Wexler, C., Maloba, M., Mabachi, N., Ndikum-Moffor, F., & Bukusi, E. (2016). Cervical cancer prevention and treatment research in Africa: a systematic review from a public health perspective. BMC women's health, 16, 1-25.

William, W., Ware, A., Basaza-Ejiri, A. H., & Obungoloch, J. (2019). A pap-smear analysis tool (PAT) for detection of cervical cancer from pap-smear images. Biomedical engineering online, 18, 1-22.

Ng’ang’a, A., Nyangasi, M., Nkonge, N. G., Gathitu, E., Kibachio, J., Gichangi, P., ... & Kyobutungi, C. (2018). Predictors of cervical cancer screening among Kenyan women: results of a nested case-control study in a nationally representative survey. BMC public health, 18, 1-10.

Momenimovahed, Z., Mazidimoradi, A., Maroofi, P., Allahqoli, L., Salehiniya, H., & Alkatout, I. (2023). Global, regional and national burden, incidence, and mortality of cervical cancer. Cancer reports, 6(3), e1756.

Anaman-Torgbor, J. A., King, J., & Correa-Velez, I. (2017). Barriers and facilitators of cervical cancer screening practices among African immigrant women living in Brisbane, Australia. European Journal of Oncology Nursing, 31, 22-29.

Ezechi, O. C., Gab-Okafor, C. V., Ostergren, P. O., & Odberg Pettersson, K. (2013). Willingness and acceptability of cervical cancer screening among HIV positive Nigerian women. BMC Public Health, 13, 1-8.

Eze, J. N., Umeora, O. U., Obuna, J. A., Egwuatu, V. E., & Ejikeme, B. N. (2012). Cervical cancer awareness and cervical screening uptake at the Mater Misericordiae Hospital, Afikpo, Southeast Nigeria. Annals of African medicine, 11(4), 238-243.

Stewart, T. S., Moodley, J., & Walter, F. M. (2018). Population risk factors for late-stage presentation of cervical cancer in sub-Saharan Africa. Cancer Epidemiology, 53, 81-92.

Vermandere, H., Naanyu, V., Mabeya, H., Vanden Broeck, D., Michielsen, K., & Degomme, O. (2014). Determinants of acceptance and subsequent uptake of the HPV vaccine in a cohort in Eldoret, Kenya. PloS one, 9(10), e109353.

Mengesha, M. B., Chekole, T. T., & Hidru, H. D. (2023). Uptake and barriers to cervical cancer screening among human immunodeficiency virus-positive women in Sub Saharan Africa: a systematic review and meta-analysis. BMC women's health, 23(1), 338.