COVID-19 is a severe respiratory infection caused by coronavirus 2.(SARS-CoV-2). Even while SARS-CoV-2 predominantly affects the respiratory system, it can cause problems for other important organs as well. Multiple novel variations of concern have appeared since the beginning of the SARS-CoV-2 pandemic, including the Alpha (B. 1.1. 7), Beta (B. 1.351), Gamma (P. 1), Delta (B. 1.617. 2), and Omicron (B. 1.1. 529), all of which are linked to increased transmissibility and severity. Both the newly discovered variants and the most recent innovative treatments for the treatment of COVID-19 are discussed in this work. Care for people with this disease is discussed, with an emphasis on the need of clinical interprofessional teams, government health organisations, and community involvement.